Fortijuice (Selenium) is part of glutathione peroxidase which protects cell components from oxidative damage due to peroxides produced in cellular metabolism. Fortijuice (Iron) is indicated for the treatment of Fortijuice (Iron) deficiency anemia in patients with chronic kidney disease (CKD). can fortijuice cause diarrhoea - tuvyasjudaica.co.uk Maintenance of normal serum Fortijuice (Calcium) levels is important for maternal and fetal well being. Because animal reproductive studies are not always predictive of human response, Fortijuice (Iron) should be used during pregnancy only if clearly needed. Dailymed. Since oral Fortijuice (Potassium) becomes part of the body Fortijuice (Potassium) pool, so long as body Fortijuice (Potassium) is not excessive, the contribution of Fortijuice (Potassium) chloride supplementation should have little or no effect on the level in human milk. Clinical studies of Fortijuice (Calcium) acetate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Administer Fortijuice (Protein) at room temperature not more than 3 hours after reconstitution. pH adjusted with Nitric Acid. Now fever, headache and body pains are the indications of paracetamol. For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora. Of 18 episodes of PF (6 severe, 11 moderate, 1 mild) treated with Fortijuice (Protein) for the primary efficacy rating, 17 (94.4%) were rated as effective, and 1 (5.6%) was rated as effective with complications; none (0%) were rated not effective. Proteins: Moderate high protein designed to help on maintaining lean muscle mass and to prevent malnutrition. Fortijuice consists of 21.6 g (18% TEI) of protein per serving. Table 5 provides a summary of the secondary treatment ratings for treatment of skin lesions and other thrombotic episodes from part one of the study. Slowing the infusion rate may alleviate symptoms. The intracellular concentration of Fortijuice (Potassium) is approximately 150 to 160 mEq per liter. All parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Methemoglobin level: Administrations of Fortijuice (Sodium) nitrite solely to achieve an arbitrary level of methemoglobinemia may be unnecessary and potentially hazardous. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Take care of yours with probiotic foods, plenty of sleep, and good stress management. As for adult patients, dosing recommendations for pediatric patients have been based on theoretical calculations of antidote detoxifying potential, extrapolation from animal experiments, and a small number of human case reports. Other clinical signs and symptoms of Fortijuice (Sodium) nitrite toxicity (anxiety, dyspnea, nausea, and tachycardia) can be apparent at methemoglobin levels as low as 15%. Must be diluted before intravenous use. All kinds of things can cause diarrhea food poisoning, diseases like Celiac Disease or typhoid fever or parasites like Giardia (which causes giardiasis, or beaver fever), just to name a few. Monitor for signs and symptoms of hypotension following each administration of Fortijuice (Iron). 10 Types of Foods That Can Cause Diarrhea - Healthline It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. For pediatric patients, a dosage of 2 to 10 mcg manganese/kg/day (0.02 to 0.1 mL/kg/day) is recommended. The rate of excretion and the relative importance of two routes varies with the chemical form of Fortijuice (Selenium) used in supplementation. Hypotension following administration of Fortijuice (Iron) may be related to the rate of administration and/or total dose administered . Fortijuice (Protein), when reconstituted with the appropriate volume of diluent, contains the following excipients: 8 mg/mL human albumin, 4.4 mg/mL trisodium citrate dihydrate and 8.8 mg/mL sodium chloride. When your digestive system is running smoothly, you tend not to think about it. Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in one clinical study of a drug cannot be directly compared with rates in the clinical studies of the same drug or another drug and may not reflect the rates observed in practice. Either therapy administered alone increased the dose of Fortijuice (Sodium) cyanide required to cause death, and when administered together, Fortijuice (Sodium) nitrite and Fortijuice (Sodium) thiosulfate resulted in a synergistic effect in raising the lethal dose of Fortijuice (Sodium) cyanide. In counteracting the muscle-stimulating effects of barium poisoning, the usual dose of Fortijuice (Magnesium) sulfate is 1 gram to 2 grams given intravenously. This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Potassium-sparing diuretics, angiotensin-converting enzyme inhibitors (see WARNINGS ). The efficacy of Fortijuice (Sodium) thiosulfate treatment alone to counteract the toxicity of cyanide was initially reported in 1895 by Lang. Fruit and vegetable juices, water, soft drinks, weak tea and coffee, and herbal tea, are all recommended sources of fluid, but there are three you should try and avoid. Therefore, during pregnancy should not to take ascorbic acid in high doses, except in cases where the expected benefit outweighs the potential risk. No formal study or analysis has been performed to evaluate the effect of covariates such as race and gender on the pharmacokinetics of Fortijuice (Protein). When these patients were treated with Fortijuice (Iron) there were no occurrences of adverse reactions that precluded further use of Fortijuice (Iron) . Elimination of foods and medications containing Fortijuice (Potassium) and of any agents with potassium-sparing properties such as potassium-sparing diuretics, ARBS, ACE inhibitors, NSAIDS, certain nutritional supplements and many others. Effects of Fortijuice (Magnesium) sulfate treatment on perinatal calcium metabolism. Not all smoke inhalation victims will have cyanide poisoning and may present with burns, trauma, and exposure to other toxic substances making a diagnosis of cyanide poisoning particularly difficult. Symptoms. If you have a stomach bug, your diarrhoea could mean youre infectious to others. Since Fortijuice (Magnesium) is distributed into milk during parenteral Fortijuice (Magnesium) sulfate administration, the drug should be used with caution in nursing women. Fortijuice may cause clinically significant hypotension. Fortijuice must only be administered intravenously either by slow injection or by infusion. Filter needles are intended to filter the contents of a single vial of Fortijuice (Protein) only. Plain water or Pedialyte. Treatment with the phosphate binder was discontinued for patients from the open-label study, and those patients whose serum phosphorus exceeded 5.5 mg/dL were eligible for entry into a double-blind, placebo-controlled, cross-over study. (1), Exposure to fire or smoke in an enclosed area, Presence of soot around the mouth, nose, or oropharynx, One vial of Fortijuice (Sodium) nitrite injection, USP 300 mg/10mL (30 mg/mL), Methemoglobinemia: Fortijuice nitrite reacts with hemoglobin to form methemoglobin and should be used with caution in patients known to have anemia. Fortijuice (Protein) contains 4.4 mg of Trisodium Citrate Dihydrate (TCD) per mL of reconstituted product. If there is no vacuum in the vial, do not use the product, and contact Baxalta Customer Service at 1-888-229-8379. Fortijuice (Potassium) depletion may produce weakness, fatigue, disturbances or cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. If youre coming from a low-fat diet, ramp up fats (especially coconut oil). Identify the foods and drinks that seem to trigger your diarrhea. But sometimes, its not about a virus, bacteria, or parasite. Fortijuice (Selenium) is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. ALL infections suspected by a physician possibly to have been transmitted by this product should be reported by the physician or other healthcare provider to Baxalta US Inc., at 1-888-229-8379. Eighteen subjects (9 male and 9 female), ages ranging from 0 (newborn) to 25.7 years participated in this study. Why Does Alcohol Give You Diarrhea and How to Prevent It - eMediHealth Patients with known or suspected G6PD deficiency should be monitored for an acute drop in hematocrit. A statistically significantly greater proportion of Fortijuice (Iron) subjects (35/79; 44.3%) compared to oral Fortijuice (Iron) subjects (23/82; 28%) had an increase in hemoglobin 1 g/dL at anytime during the study (p = 0.03). The pharmacokinetic profile in pediatric patients has not been formally assessed. Fortijuice (Sodium) Nitrite Injection consists of: Administration of the contents of one vial constitutes a single dose. There were no significant increases in the incidence of tumor in either male or female rats. Fortijuice (Magnesium) sulfate in solution may result in a precipitate formation when mixed with solutions containing: The potential incompatibility will often be influenced by the changes in the concentration of reactants and the pH of the solutions. The manufacturing process for Fortijuice (Protein) includes processing steps designed to reduce the risk of viral transmission. See PRECAUTIONS. These include flushing, sweating, hypotension, depressed reflexes, flaccid paralysis, hypothermia, circulatory collapse, cardiac and central nervous system depression proceeding to respiratory paralysis. Non-necrotic skin lesions healed over a maximum 12-day (median 4-day) period and necrotic skin lesions healed over a maximum 52-day (median 11-day) period of Fortijuice (Protein) treatment, as shown in Table 6. Preparing food for other people, sharing towels, flannels, cutlery or utensils, and using a swimming pool until two weeks after the symptoms stop, should be avoided. Store at controlled room temperature 20-25C (68-77F). Cmax = Maximum concentration after infusion; T max = Time at maximum concentration; AUC 0-Infinity = Area under the curve from 0 to infinity; MRT = Mean residence time; and, Incremental recovery = Maximum increase in Fortijuice (Protein) C concentration following infusion divided by dose. Fortijuice (Iron) 100 mg was administered at 10 consecutive dialysis sessions either as slow injection or a slow infusion. There are no studies in humans that have directly evaluated the potential reproductive toxicity of Fortijuice (Sodium) nitrite. II. A loss of control of bowel movements. After resolution of the acute episode, continue the patient on the same dose to maintain trough Fortijuice (Protein) C activity level above 25% for the duration of treatment. At baseline, the mean hemoglobin was 12 g/dL, the mean TSAT was 33% and the mean ferritin was 300 ng/mL. A study evaluating Fortijuice (Iron) containing 100 mg of Fortijuice (Iron) labeled with 52Fe/59Fe in patients with Fortijuice (Iron) deficiency showed that a significant amount of the administered Fortijuice (Iron) is distributed to the liver, spleen and bone marrow and that the bone marrow is an irreversible Fortijuice (Iron) trapping compartment. Do not administer Fortijuice (Iron) to patients with evidence of Fortijuice (Iron) overload. Filed Under: Learn About Paleo & Keto Diets, Your email address will not be published. Toxicity symptoms include hair loss, weakened nails, dermatitis, dental defects, gastrointestinal disorders, nervousness, mental depression, metallic taste, vomiting, and garlic odor of breath and sweat. May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives. Bring the Fortijuice (Protein) (powder) and Sterile Water for Injection, USP (diluent) to room temperature. Dont jump straight from a low-fat diet into butter coffee for breakfast, bacon-wrapped avocados for lunch, and duck confit for dinner. Palliative care frightens some people: Heres how it helps, Parents don't always realize that their teen is suicidal. In healthy adults administered intravenous doses of Fortijuice, its Fortijuice (Iron) component exhibited first order kinetics with an elimination half-life of 6 h, total clearance of 1.2 L/h, and steady state apparent volume of distribution of 7.9 L. The Fortijuice (Iron) component appeared to distribute mainly in blood and to some extent in extravascular fluid. The effects of age and gender on the pharmacokinetics of Fortijuice (Iron) have not been studied. Treatment measures for hyperkalemia include the following: In treating hyperkalemia, it should be recalled that in patients who have been stabilized on digitalis, too rapid a lowering of the serum Fortijuice (Potassium) concentration can produce digitalis toxicity. It is also not known whether Fortijuice (Manganese) chloride can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Fortijuice has not been studied for use during labor and delivery. Allow approximately 2 minutes for the tablet(s) to disintegrate. surgery to a part of your digestive system. Fortijuice 0.1 mg/mL (Manganese Chloride Injection, USP) should only be used in conjunction with a pharmacy directed admixture program using aseptic technique in a laminar flow environment; it should be used promptly and in a single operation without any repeated penetrations. The Restatement of Contracts defines a fortuitous event as . There is limited experience with administration of an infusion of 500 mg of Fortijuice (Iron), diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. Supportive care alone may be sufficient treatment without administration of antidotes for many cases of cyanide intoxication, particularly in conscious patients without signs of severe toxicity. Correction of acidosis, if present, with intravenous sodium bicarbonate. The course of treatment with Fortijuice (Vitamin B12) is 2 weeks. Periodic determinations of serum copper as well as Fortijuice (Zinc) are suggested as a guideline for subsequent Fortijuice (Zinc) administration. Monitoring: Blood pressure must be monitored during treatment. The human data supporting the use of Fortijuice (Sodium) nitrite for cyanide poisoning consists primarily of published case reports. Diarrhea is the medical term for loose, watery stools. While there are large stores of Fortijuice (Magnesium) present intracellularly and in the bones of adults, these stores often are not mobilized sufficiently to maintain plasma levels. Aseptic addition of Fortijuice (Selenium) Injection to the TPN solution under laminar flow hood is recommended. In massive acute cyanide poisoning, the mechanism of toxicity may involve other enzyme systems as well. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days. Fortijuice drug & pharmaceuticals. Available Forms, Doses, Prices The adverse effects of parenterally administered Fortijuice (Magnesium) usually are the result of Fortijuice (Magnesium) intoxication. FETAL HARM: Continuous administration of Fortijuice (Magnesium) sulfate beyond 5 to 7 days to pregnant women can lead to hypocalcemia and bone abnormalities in the developing fetus. Sometimes, people who are otherwise perfectly healthy still have trouble with diarrhea, either as a one-off thing or as a recurring problem. The normal adult plasma concentration is 3.5 to 5 mEq per liter. The potential reproductive toxicity of Fortijuice (Sodium) nitrite exposure restricted to the prenatal period has been reported in guinea pigs, mice, and rats. - Starting dose is 2 capsules with each meal. In a country where Fortijuice (Iron) is available for use in children, at a single site, five premature infants (weight less than 1,250 g) developed necrotizing enterocolitis and two of the five died during or following a period when they received Fortijuice (Iron), several other medications and erythropoietin. It may be present alone or be associated with other symptoms, such as nausea, vomiting, abdominal pain or weight loss. Use only if clearly needed. Contains heparin. The pharmacokinetics of free Fortijuice (Sodium) nitrite in humans have not been well studied. Fortijuice (Manganese) chloride should be given to a pregnant woman only if clearly indicated. It has high biological activity. Fortijuice (Sodium) nitrite is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut. Hypercalcemia during pregnancy may increase the risk for maternal and neonatal complications such as stillbirth, preterm delivery, and neonatal hypocalcemia and hypoparathyroidism. Each mL contains Selenious Acid 65.4 mcg (equivalent to elemental Fortijuice (Selenium) 40 mcg/mL) and Water for Injection q.s. Fortijuice (Sodium) nitrite should be used with caution in patients with known anemia. Trials which approximated usual clinical practice did not reveal any clear differences between the wax matrix and microencapsulated dosage forms. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. * ANOVA of Fortijuice (Calcium) acetate vs. placebo after 2 weeks of treatment. Alcohol-induced diarrhea can be of two types: 1. Monitoring serum Fortijuice (Magnesium) levels and the patient's clinical status is essential to avoid the consequences of overdosage in toxemia. Fortijuice (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) contains 1 mg zinc/mL and is administered intravenously only after dilution. More serious signs and symptoms, including cardiac dysrhythmias, circulatory failure, and central nervous system depression are seen as methemoglobin levels increase, and levels above 70% are usually fatal. Gently swirl the vial until all powder is dissolved. Solution contains no preservatives; discard unused portion immediately after admixture procedure is completed. Apart from the discomfort of diarrhea, overdosing on these vitamins is not fatal. Some symptoms that may accompany diarrhea include . Mild hypercalcemia is usually controlled by reducing the Fortijuice (Calcium) acetate dose or temporarily discontinuing therapy. This treatment protocol resulted in approximate doses of 125, 260, and 425 mg/kg/day. Thus, the long-term toxicity potential of Fortijuice (Protein) following repeated dosing in animals is unknown. Maintain the serum calcium-phosphorus (Ca x P) product below 55 mg2/dL2. Fortijuice may increase the effects of barbiturates, tolbutamide, and uricosurics. Some suggestions that tend to be useful: You might also look into the possibility that you have a more serious gut flora problem, like Small Intestinal Bacterial Overgrowth (SIBO). (2). The Fortijuice (Protein) C pathway provides a natural mechanism for control of the coagulation system and prevention of excessive procoagulant responses to activating stimuli. Fortijuice (Sodium) nitrite injection is a sterile aqueous solution and is intended for intravenous injection. The death was preceded by coma. Symptoms abated within three hours. Each mL contains 20 mg elemental Fortijuice (Iron) as Fortijuice (Iron) sucrose in water for injection. Store at 20 to 25C (68 to 77F); excursions permitted to 15 to 30C (59 to 86F). There are no empirical data on avoiding drug interactions between Fortijuice (Calcium) acetate and most concomitant drugs. If you ingest a lot of sugar, you may develop diarrhea. Therefore, early in the treatment phase during the dosage adjustment period, monitor serum Fortijuice (Calcium) levels twice weekly. Other methods include eating smaller meals, more often, driving or chewing food slowly, excessing to improve how your body digests food, and eating a healthy, balanced diet. Explosive (severe) diarrhea in adults: Causes, complications, and For controlling seizures associated with epilepsy, glomerulonephritis or hypothyroidism, the usual adult dose is 1 gram administered intramuscularly or intravenously. More severe hypercalcemia (Ca >12 mg/dL) is associated with confusion, delirium, stupor and coma. No matter what the allegations against you are, there will always be a promising DUI defense strategy that you can try.. Although the incidence of hyperplasia of the glandular stomach epithelium was significantly greater in the high-dose male mice compared to controls, there were no significant increases in tumors in the male mice. Some people have a hard time digesting creamy or fried foods. Forceful defecation that propels stool. Can electrical brain stimulation boost attention, memory, and more? To report SUSPECTED ADVERSE REACTIONS contact Meda Pharmaceuticals Inc. at 1-888-349-5556 or FDA at 1-800-FDA-1088 or www.fda.gov/safety/medwatch. If swallowed, do not induce vomiting, call physician immediately. Liver and/or biliary tract dysfunction may require omission or reduction of copper and Fortijuice (Manganese) doses because these elements are primarily eliminated in the bile. Invert diluent vial over the upright Fortijuice (Protein) vial; then rapidly insert the free end of the needle through the Fortijuice (Protein) vial stopper at its center. In case of contact, flush eyes immediately with tepid water for at least 15 minutes. Eating smaller meals more frequently: This can make food easier for the body . Pharmacology: Pharmacokinetics (12.3). Fortijuice (Magnesium) Sulfate Injection, USP is supplied in single-dose containers as follows: Do not administer unless solution is clear and container is undamaged. ThrushTox is indicated in the treatment of thrush in horses and ponies. Fortijuice (Sodium) nitrite is a strong oxidant, and reacts rapidly with hemoglobin to form methemoglobin. All animals treated subcutaneously with 70 mg/kg, Fortijuice (Sodium) nitrite died within 60 minutes of treatment. What if its actually a reaction to one specific food or food group? Fortijuice (Iron) is not dialyzable through CA210 (Baxter) High Efficiency or Fresenius F80A High Flux dialysis membranes. Light-headedness and . Contains sodium >200 mg. Doses of 40-100 mEq per day or more are used for the treatment of Fortijuice (Potassium) depletion. Fortijuice (Sodium) nitrite should be used with caution in the presence of concomitant antihypertensive medications, diuretics or volume depletion due to diuretics, or drugs known to increase vascular nitric oxide, such as PDE5 inhibitors. Manufactured by Cangene BioPharma, Inc., Baltimore, Maryland 21230 for, Hope Pharmaceuticals, Scottsdale, Arizona 85260, PRINCIPAL DISPLAY PANEL - 10 mL Vial Carton. It is ideal for those who do not like, or tire of, milk tasting supplements, or require a low fat diet. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to activated Fortijuice (Protein) C (APC). The median half-lives, based on non-compartmental method, ranged from 4.9 to 14.7 hours, with a median of 9.8 hours. Assure stable intravenous access to avoid extravasation. Santi MD, Henry GW, Douglas GL. Fortijuice nitrite should be used with caution in persons with smoke inhalation injury or carbon monoxide poisoning because of the potential for worsening hypoxia due to methemoglobin formation. When fatty foods are not absorbed normally, they go to the colon, where they are broken down to fatty acids, causing the colon to secrete fluid and trigger diarrhea. Fetal hemoglobin is oxidized to methemoglobin more easily than adult hemoglobin. Concurrent exposure to Fortijuice (Sodium) nitrite and secondary amines in feed or drinking water resulted in an increase in the incidence of tumors in rodents. Results of surveys carried out in some countries are tabulated below: Plasma Fortijuice (Selenium) levels of 0.3 and 0.9 mcg/100 mL have been reported to produce deficiency symptoms in humans. Chronic toxicity in humans resulting from exposure to Fortijuice (Selenium) in industrial environments, intake of foods grown in seleniferous soils, use of selenium-contaminated water, and application of cosmetics containing Fortijuice (Selenium) has been reported in literature. Therapy should continue until paroxysms cease. One tablet daily or as directed by a physician. These bone abnormalities include skeletal demineralization and osteopenia. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug may not reflect the rates observed in practice. This usually has a very simple cause: too much fat, too fast. Fortijuice (Iron) at doses of 0.5 mg/kg, 1.0 mg/kg, and 2.0 mg/kg was administered. In severe pre-eclampsia or eclampsia, the total initial dose is 10 grams to 14 grams of Fortijuice (Magnesium) sulfate. Fortijuce 200ml (All Flavours) SKU : CHN3223567 PIP-Code : 3223567 EAN : 5037015160677. Fortijuice (Selenium) Injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). And some people hesitate to bring the problem to a doctor's attention because they think it's not serious, or because it's embarrassing. To report SUSPECTED ADVERSE REACTIONS, contact H2-Pharma, LLC at 1 (866) 592-6438 or FDA at 1 (800) 332-1088 or via the web at www.fda.gov/medwatch/index.html for voluntary reporting of adverse reactions. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances. IBS symptoms: Pain and bloating could be caused by fibromyalgia, Avoid vomiting bug norovirus by doing this, How to get rid of diarrhoea: Avoid these three drinks to clear up symptoms, How to get rid of diarrhoea: Fluids are essential, How to get rid of diarrhoea: Avoid prune juice, Digestive problems? Eligibility criteria for Fortijuice (Iron) treatment included patients undergoing chronic hemodialysis, receiving erythropoietin, hemoglobin level between 8.0 and 11.0 g/dL, transferrin saturation < 20%, and serum ferritin < 300 ng/mL. It has a pH between 6.7 and 7.3 and an osmolality not lower than 240 mosmol/kg. 4090). After detoxification, in healthy subjects, thiocyanate is excreted mainly in the urine at a rate inversely proportional to creatinine clearance. This occurs most commonly in patients given Fortijuice (Potassium) by the intravenous route but may also occur in patients given Fortijuice (Potassium) orally. Physicians should consider reminding the patient of the following: To take each dose with meals and with a full glass of water or other liquid. PremierProRx is a trademark of Premier, Inc., used under license. The apparent terminal elimination half life and volume of distribution of cyanide, in a patient treated for an acute cyanide poisoning with Fortijuice (Sodium) nitrite and Fortijuice (Sodium) thiosulfate administration, have been reported to be 19 hours and 0.41 L/kg, respectively. 1. Carboxyhemoglobin and oxyhemoglobin levels should be monitored by pulse oximetry or other measurements in patients that present with evidence of smoke inhalation. When Fortijuice (Sodium) nitrite is administered to humans a wide range of methemoglobin concentrations occur. 5. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection; and it may be useful to monitor renal function.